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John Gurdon Quotes
John Gurdon Quotes
John Gurdon
English
Scientist
Born:
Oct 2
,
1933
Been
Cells
People
Will
Work
You
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It is particularly pleasing to see how purely basic research, originally aimed at testing the genetic identity of different cell types in the body, has turned out to have clear human health prospects.
John Gurdon
Health
Research
Types
Pleasing
Out
See
Purely
Clear
Prospects
Genetic
Particularly
Identity
How
Testing
Cell
Human
Different
Turned
Human Health
Body
Originally
Basic
Basic Research
As a brand new graduate student starting in October 1956, my supervisor Michail Fischberg, a lecturer in the Department of Zoology at Oxford, suggested that I should try to make somatic cell nuclear transplantation work in the South African frog Xenopus laevis.
John Gurdon
Work
Try
Supervisor
Student
New
Make
October
Lecturer
South
South African
Brand
Brand New
Department
Cell
Frog
Graduate
Graduate Student
Oxford
African
Should
Nuclear
Suggested
Starting
Zoology
Nuclear transplantation is a technique that has enormously facilitated the analysis of these interactions between nucleus and cytoplasm.
John Gurdon
Analysis
Between
Interactions
Nuclear
Technique
There is no doubt that I was blessed with a considerable amount of luck.
John Gurdon
Blessed
Doubt
Luck
Considerable
No Doubt
Amount
Within one year of starting work, I had found that the nucleus of an endoderm cell from an advanced tadpole was able to yield some normal development up to the nuclear transplant tadpole stage.
John Gurdon
Work
Year
Stage
Able
Some
Had
Advanced
Development
Within
Normal
Up
Yield
Cell
Transplant
Found
Nuclear
Starting
I wondered whether the nuclear transfer techniques could be used to introduce purified macro-molecules into an egg, and hence into embryonic cells.
John Gurdon
Introduce
Embryonic
Purified
Could
Wondered
Egg
Cells
Transfer
Whether
Used
Hence
Nuclear
Techniques
For my part, I have worked all my life with eggs and embryos of frogs. Compared to other small animals, these have figured prominently in the world of literature.
John Gurdon
Life
World
My Life
Animals
Other
All My Life
Embryos
Small
Part
Eggs
Frogs
Literature
Worked
Figured
Compared
Shinya Yamanaka's work has involved mice and human cells, and advances the prospect of providing new cells or body parts for patients.
John Gurdon
Work
Advances
Prospect
New
Involved
Parts
Providing
Mice
Cells
Human
Patients
Body
The earliest example known to me of replaced body parts is exemplified by a Mayan skull dating back to 1400 BC. In this skull, false teeth made of stone had been implanted.
John Gurdon
Me
Made
Example
Back
Teeth
Dating
Had
Known
Parts
Been
False
Replaced
Stone
Body
Skull
Earliest
I get into lab early and leave a bit early, too. So I like to have an hour or two before everybody comes in.
John Gurdon
Before
Too
Everybody
Bit
Hour
Like
Leave
Lab
Get
Early
Two
Once the principle is there, that cells have the same genes, my own personal belief is that we will, in the end, understand everything about how cells actually work.
John Gurdon
Work
Will
Own
Everything
Once
About
My Own
Genes
Principle
Understand
How
End
Personal
Same
Cells
In The End
Belief
Actually
There's a danger of some of the best people saying, 'I don't want a career in science.'
John Gurdon
Saying
Best
Science
People
Danger
Some
Want
Career
If you explain to a patient what can be done and what might be the downsides, let the patient choose; don't have ethicists, priests, or doctors say you may or may not have replacement cells.
John Gurdon
You
Doctors
Patient
Say
Priests
Replacement
Done
Cells
May
Explain
Might
Choose
I must have been born with a strong attraction toward, and possibly even an aptitude for, doing things on a small scale.
John Gurdon
Strong
Aptitude
Scale
Possibly
Must
Born
Small
Small Scale
Toward
Attraction
Doing
Been
Even
Things
I remember that, at an early age, I spent many months making a three-masted sailing boat with rigging in a half-walnut shell.
John Gurdon
Age
Remember
Months
Spent
Shell
Making
Sailing
Boat
Many
Early
Early Age
In principle. what is done is to take the nucleus out of a cell with a very fine micro-pipette or needle and introduce it into an egg. That had been done with amphibians a long time ago, and then there was a long pause of many years before people were clever enough to make that work in the sheep.
John Gurdon
Work
Time
People
Long
Long Time
Clever
Sheep
Before
Enough
Out
Introduce
Fine
Take
Had
Long Time Ago
Make
Principle
Were
Been
Years
Very
Egg
Cell
Done
Pause
Then
Many
Needle
The aim of a nuclear-transplant experiment is to insert the nucleus of a specialized cell into an unfertilized egg whose nucleus has been removed.
John Gurdon
Experiment
Aim
Has-Been
Insert
Been
Egg
Cell
Specialized
Whose
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